ID LINK | NAME | STRUCTURE CAS | CLOGP | CLOGS | MW | THERAPEUTIC AREA |
---|---|---|---|---|---|---|
FDBD00276 | Progesterone |
![]() 57-83-0 |
4.491 | -4.382 | 314.462 | For progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used for the reduction of the incidence of endometrial hyperplasia and the attendant risk of endometrial carcinoma in postmenopausal women receiving estrogen replacement therapy, as well as treatment of abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology such as fibroids or uterine cancer. |
FDBD00277 | Phenylpropanolamine |
![]() 14838-15-4 |
1.145 | -1.173 | 151.206 | For the treatment of nasal congestion, control of urinary incontinence, priapism and obesity. |
FDBD00278 | Sorafenib |
![]() 284461-73-0 |
3.777 | -7.088 | 464.825 | Sorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma. |
FDBD00279 | Zoledronate |
![]() 118072-93-8 |
-3.879 | 2.429 | 272.090 | For the treatment of hypercalcemia of malignancy. Also for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. In May of 2007, the drug was approved for treatment of Paget's Disease. |
FDBD00281 | Nisoldipine |
![]() 63675-72-9 |
2.646 | -4.648 | 388.414 | For the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents. |
FDBD00282 | Eszopiclone |
![]() 138729-47-2 |
0.317 | -2.992 | 388.808 | For the treatment of insomnia. |
FDBD00283 | Ceruletide |
![]() 17650-98-5 |
0.220 | -7.210 | 1352.405 | Caerulein stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. As such, it is used in paralytic ileus and as diagnostic aid in pancreatic malfunction. |
FDBD00284 | Alprazolam |
![]() 28981-97-7 |
4.164 | -5.433 | 308.765 | For the management of anxiety disorder or the short-term relief of symptoms of anxiety and for the treatment of panic disorder, with or without agoraphobia. |
FDBD00285 | Dexbrompheniramine |
![]() 132-21-8 |
4.037 | -5.131 | 319.239 | For treatment and relief of symptoms of allergies, hay fever, and colds. |
FDBD00286 | Gentian Violet |
![]() 14426-25-6 |
0.918 | -5.442 | 372.526 | For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive). |
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