| ID LINK | NAME | STRUCTURE CAS | CLOGP | CLOGS | MW | THERAPEUTIC AREA |
|---|---|---|---|---|---|---|
| FDBD00255 | Timolol |
 26839-75-8 |
1.772 | -2.375 | 316.420 | In its oral form it is used to treat high blood pressure and prevent heart attacks, and occasionally to prevent migraine headaches. In its opthalmic form it is used to treat open-angle and occasionally secondary glaucoma. |
| FDBD00256 | Treprostinil |
 81846-19-7 |
4.087 | -4.123 | 390.513 | For use as a continuous subcutaneous infusion or intravenous infusion (for those not able to tolerate a subcutaneous infusion) for the treatment of pulmonary arterial hypertension in patients with NYHA Class II-IV symptoms to diminish symptoms associated with exercise. |
| FDBD00257 | Colestipol |
 26658-42-4 |
-0.944 | -2.558 | 189.302 | For use, as adjunctive therapy to diet, for the reduction of elevated serum total and LDL-C in patients with primary hypercholesterolemia (elevated LDL-C) who do not respond adequately to diet. |
| FDBD00258 | Trihexyphenidyl |
 144-11-6 |
4.233 | -4.073 | 301.466 | Indicated for the treatment of parkinson's disease and extrapyramidal reactions caused by drugs. |
| FDBD00259 | Palonosetron |
 135729-56-5 |
2.821 | -3.403 | 296.407 | For the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy, as well as prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy. Also used for the prevention of postoperative nausea and vomiting for up to 24 hours post operation. |
| FDBD00260 | Dydrogesterone |
 152-62-5 |
4.084 | -3.915 | 312.446 | Used to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency. Also used to prevent natural abortion in patients who have a history of habitual abortions. |
| FDBD00261 | Mexiletine |
 31828-71-4 |
2.446 | -2.938 | 179.259 | For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation. |
| FDBD00262 | Dexrazoxane |
 24584-09-6 |
-0.680 | -1.272 | 268.269 | For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg/m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines. |
| FDBD00263 | Amlodipine |
 88150-42-9 |
3.213 | -5.013 | 408.876 | For the treatment of hypertension and chronic stable angina. |
| FDBD00264 | Oxyphencyclimine |
 125-53-1 |
3.498 | -3.475 | 344.448 | For the treatment of peptic ulcer disease and the relief of smooth muscle spasms in gastrointestinal disorders. |
2911 ,
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