Responsive image

Common name


Mexiletine

IUPAC name


1-(2,6-dimethylphenoxy)propan-2-amine

SMILES


CC(N)COC1=C(C)C=CC=C1C

Compound class


Anti-Arrhythmia Agents; Voltage-Gated Sodium Channel Blockers; Cardiovascular System; Antiarrhythmics, Class I and Iii; Cardiac Therapy; Antiarrythmics, Class I and Iii; Antiarrhythmics, Class Ib; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors;

Therapeutic area


For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.

Common name


Mexiletine

IUPAC name


1-(2,6-dimethylphenoxy)propan-2-amine

SMILES


CC(N)COC1=C(C)C=CC=C1C

INCHI


InChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3

FORMULA


C11H17NO

Responsive image

Common name


Mexiletine

IUPAC name


1-(2,6-dimethylphenoxy)propan-2-amine

Molecular weight


179.259

clogP


2.446

clogS


-2.938

HBond Acceptor


1

HBond Donor


2

Total Polar
Surface Area


35.25

Number of Rings


1

Rotatable Bond


3

Drug ID Common name Structure CAS SMILE Frequency
FDBF00040 ethanamine Responsive image CCN 0.0677
FDBF00208 propan-2-amine Responsive image CC(N)C 0.0210
FDBF00502 m-xylene Responsive image c1c(cccc1C)C 0.0144
FDBF00831 2,6-dimethylphenol Responsive image c1(c(cccc1C)C)O 0.0010
FDBF00832 2-methoxy-1,3-dimethyl-benzene Responsive image c1(c(cccc1C)C)OC 0.0007
6 , 1