Responsive image

Common name


Fluvoxamine

IUPAC name


(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine

SMILES


COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F

Compound class


Antidepressive Agents, Second-Generation; Anti-Anxiety Agents; Serotonin Uptake Inhibitors; Nervous System; Antidepressants; Psychoanaleptics; Selective Serotonin Reuptake Inhibitors; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors; Combined Inhibitors of CYP3A4 and P-glycoprotein;

Therapeutic area


For management of depression and for Obsessive Compulsive Disorder (OCD). Has also been used in the management of bulimia nervosa.

Common name


Fluvoxamine

IUPAC name


(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine

SMILES


COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F

INCHI


InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3

FORMULA


C15H21F3N2O2

Responsive image

Common name


Fluvoxamine

IUPAC name


(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine

Molecular weight


318.335

clogP


4.112

clogS


-4.690

HBond Acceptor


3

HBond Donor


2

Total Polar
Surface Area


56.84

Number of Rings


1

Rotatable Bond


10

Drug ID Common name Structure CAS SMILE Frequency
FDBF00040 ethanamine Responsive image CCN 0.0677
FDBF00160 N-ethylhydroxylamine Responsive image CCNO 0.0007
FDBF00161 N-benzylhydroxylamine Responsive image c1(ccccc1)CNO 0.0007
FDBF00163 N-methoxyethanamine Responsive image CCNOC 0.0007
FDBF00166 N-[(1S)-1-phenylethyl]hydroxylamine Responsive image CC(c1ccccc1)NO 0.0003
FDBF00169 1-methoxypropane Responsive image CCCOC 0.0062
FDBF00172 N-butylhydroxylamine Responsive image C(CCNO)C 0.0003
FDBF00176 N-methoxy-1-phenyl-propan-1-imine Responsive image CON=C(CC)c1ccccc1 0.0003
FDBF00177 fluoroform Responsive image FC(F)F 0.0704
FDBF00178 N-methylhydroxylamine Responsive image ONC 0.0010
25 , 3