Responsive image

Common name


Fluvoxamine

IUPAC name


(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine

SMILES


COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F

Compound class


Antidepressive Agents, Second-Generation; Anti-Anxiety Agents; Serotonin Uptake Inhibitors; Nervous System; Antidepressants; Psychoanaleptics; Selective Serotonin Reuptake Inhibitors; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors; Combined Inhibitors of CYP3A4 and P-glycoprotein;

Therapeutic area


For management of depression and for Obsessive Compulsive Disorder (OCD). Has also been used in the management of bulimia nervosa.

Common name


Fluvoxamine

IUPAC name


(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine

SMILES


COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F

INCHI


InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3

FORMULA


C15H21F3N2O2

Responsive image

Common name


Fluvoxamine

IUPAC name


(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine

Molecular weight


318.335

clogP


4.112

clogS


-4.690

HBond Acceptor


3

HBond Donor


2

Total Polar
Surface Area


56.84

Number of Rings


1

Rotatable Bond


10

Drug ID Common name Structure CAS SMILE Frequency
FDBF00005 benzene Responsive image c1ccccc1 0.2824
FDBF00007 propane Responsive image C(C)C 0.2412
FDBF00067 butane Responsive image CCCC 0.0680
FDBF00164 N-methoxy-1-phenyl-methanamine Responsive image c1(ccccc1)CNOC 0.0007
FDBF00165 N-propylhydroxylamine Responsive image CCCNO 0.0003
FDBF00167 N-[[4-(trifluoromethyl)phenyl]methyl]hydroxylamine Responsive image c1(ccc(cc1)C(F)(F)F)CNO 0.0003
FDBF00168 methoxyethane Responsive image CCOC 0.0254
FDBF00170 N-methoxypropan-1-amine Responsive image CCCNOC 0.0003
FDBF00174 N-[(1S)-1-[4-(trifluoromethyl)phenyl]ethyl]hydroxylamine Responsive image CC(c1ccc(cc1)C(F)(F)F)NO 0.0003
FDBF00175 1-methoxybutane Responsive image C(CCC)OC 0.0027
25 , 3