IUPAC name
2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
SMILES
FC(F)OC(F)(F)C(F)Cl
Compound class
Anesthetics, Inhalation; Anesthetics; Nervous System; Halogenated Hydrocarbons; Anesthetics, General; CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong);
Therapeutic area
Used for the induction and maintenance of general anaesthesia during surgery and cesarean section and also used for analgesia during vaginal delivery.
Common name
Enflurane
IUPAC name
2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
SMILES
FC(F)OC(F)(F)C(F)Cl
INCHI
InChI=1S/C3H2ClF5O/c4-1(5)3(8,9)10-2(6)7/h1-2H
FORMULA
C3H2ClF5O
Common name
Enflurane
IUPAC name
2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
Molecular weight
184.492
clogP
2.670
clogS
-1.779
HBond Acceptor
1
HBond Donor
0
Total Polar Surface Area
9.23
Number of Rings
0
Rotatable Bond
3
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00359 | difluoromethanol |
|
FC(F)O | 0.0058 |
| FDBF00370 | difluoromethane |
|
FCF | 0.0151 |
| FDBF00463 | (1R)-1-chloro-1,2,2-trifluoro-ethane |
|
ClC(F)C(F)F | 0.0003 |
| FDBF00464 | difluoromethoxy(difluoro)methane |
|
FC(F)OC(F)F | 0.0003 |
| FDBF00465 | (2R)-2-chloro-1,1,2-trifluoro-ethanol |
|
OC(C(Cl)F)(F)F | 0.0003 |
| FDBF00466 | chloro(fluoro)methane |
|
ClCF | 0.0003 |
6 ,
1
