Common name
difluoromethanol
IUPAC name
difluoromethanol
SMILES
FC(F)O
Common name
difluoromethanol
IUPAC name
difluoromethanol
SMILES
FC(F)O
INCHI
InChI=1S/CH2F2O/c2-1(3)4/h1,4H
FORMULA
CH2F2O
Common name
difluoromethanol
IUPAC name
difluoromethanol
Molecular weight
68.023
clogP
1.034
clogS
0.238
Frequency
0.0058
HBond Acceptor
1
HBond Donor
1
Total PolarSurface Area
20.23
Number of Rings
0
Rotatable Bond
0
| Drug ID | Common name | Structure CAS | Compound class | Therapeutic area |
|---|---|---|---|---|
| FDBD00101 | Pantoprazole |
|
Anti-Ulcer Agents; Proton Pump Inhibitors; Alimentary Tract and Metabolism; Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord); Drugs for Acid Related Disorders; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; CYP3A4 Inhibitors; | Short-term (up to 16 weeks) treatment of erosive esophagitis. |
| FDBD00116 | Enflurane |
|
Anesthetics, Inhalation; Anesthetics; Nervous System; Halogenated Hydrocarbons; Anesthetics, General; CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); | Used for the induction and maintenance of general anaesthesia during surgery and cesarean section and also used for analgesia during vaginal delivery. |
| FDBD00617 | Isoflurane |
|
Anesthetics, Inhalation; Anesthetics; Nervous System; Halogenated Hydrocarbons; Anesthetics, General; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); | For induction and maintenance of general anesthesia. |
| FDBD01035 | Desflurane |
|
Anesthetics, Inhalation; Anesthetics; Nervous System; Halogenated Hydrocarbons; Anesthetics, General; | For use as an inhalation agent for induction and/or maintenance of anesthesia for inpatient and outpatient surgery in adults. |
| FDBD01279 | Roflumilast |
|
Respiratory System; Drugs for Obstructive Airway Diseases; | Roflumilast is indicated as a treatment to reduce the risk of COPD exacerbations in patients with severe COPD associated with chronic bronchitis and a history of exacerbations. Roflumilast is not a bronchodilator and is not indicated for the relief of acute bronchospasm. |
| FDBD01977 | hexaflumuron |
|
Insecticide | Insecticide |
| FDBD01978 | lufenuron |
|
Insecticide | Insecticide |
| FDBD01979 | novaluron |
|
Insecticide | Insecticide |
| FDBD01980 | noviflumuron |
|
Insecticide | Insecticide |
| FDBD02243 | brofluthrinate |
|
Insecticide | Insecticide |
17 ,
2
| FRAGNAME | PDBID | SIMILIRITY | XSCORE | SMILE | HAC |
|---|---|---|---|---|---|
| 1xmu_ligand_1_3.mol2 | 1xmu | 1 | -5.49 | OC(F)F | 4 |
| 1xoq_ligand_1_3.mol2 | 1xoq | 1 | -5.48 | C(F)(F)O | 4 |
| 2fm0_ligand_1_0.mol2 | 2fm0 | 1 | -5.48 | OC(F)F | 4 |
| 4fnz_ligand_1_10.mol2 | 4fnz | 1 | -5.48 | OC(F)(F)F | 5 |
| 2fm5_ligand_1_0.mol2 | 2fm5 | 1 | -5.47 | FC(F)O | 4 |
| 3g4l_ligand_1_3.mol2 | 3g4l | 1 | -5.44 | OC(F)F | 4 |
| 1mkd_ligand_1_3.mol2 | 1mkd | 1 | -5.41 | OC(F)F | 4 |
652 ,
66
