IUPAC name
(E)-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene][(2,4-dichlorophenyl)methoxy]amine
SMILES
ClC1=CC(Cl)=C(CO\N=C(\CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
Compound class
Antifungal Agents; Genito Urinary System and Sex Hormones; Dermatologicals; Gynecological Antiinfectives and Antiseptics; Imidazole and Triazole Derivatives; Antifungals for Topical Use; Antifungals for Dermatological Use; Imidazole Derivatives; Cytochrome P-450 CYP2C19 Inducers; CYP3A4 Inhibitors;
Therapeutic area
For treatment of dermal fungal infection.
Common name
Oxiconazole
IUPAC name
(E)-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene][(2,4-dichlorophenyl)methoxy]amine
SMILES
ClC1=CC(Cl)=C(CO\N=C(\CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
INCHI
InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18-
FORMULA
C18H13Cl4N3O
Common name
Oxiconazole
IUPAC name
(E)-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethylidene][(2,4-dichlorophenyl)methoxy]amine
Molecular weight
429.127
clogP
5.907
clogS
-7.085
HBond Acceptor
3
HBond Donor
0
Total Polar Surface Area
39.41
Number of Rings
3
Rotatable Bond
6
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00011 | imidazole |
|
[nH]1ccnc1 | 0.0175 |
| FDBF00159 | N-methoxymethanamine |
|
CONC | 0.0010 |
| FDBF00160 | N-ethylhydroxylamine |
|
CCNO | 0.0007 |
| FDBF00163 | N-methoxyethanamine |
|
CCNOC | 0.0007 |
| FDBF00178 | N-methylhydroxylamine |
|
ONC | 0.0010 |
| FDBF00490 | 1-methylimidazole |
|
n1(ccnc1)C | 0.0058 |
| FDBF00491 | N-[(2,4-dichlorophenyl)methyl]hydroxylamine |
|
Clc1c(ccc(c1)Cl)CNO | 0.0003 |
| FDBF00492 | N-[(1S)-1-(2,4-dichlorophenyl)ethyl]hydroxylamine |
|
Clc1c(ccc(c1)Cl)C(NO)C | 0.0003 |
