IUPAC name
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
SMILES
CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C
Compound class
Anesthetics, Local; Anesthetics; Nervous System; Amides; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C19 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors;
Therapeutic area
For the production of local or regional anesthesia or analgesia for surgery, for oral surgery procedures, for diagnostic and therapeutic procedures, and for obstetrical procedures.
Common name
Bupivacaine
IUPAC name
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
SMILES
CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C
INCHI
InChI=1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21)
FORMULA
C18H28N2O
Common name
Bupivacaine
IUPAC name
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
Molecular weight
288.428
clogP
3.815
clogS
-4.808
HBond Acceptor
2
HBond Donor
1
Total Polar Surface Area
32.34
Number of Rings
2
Rotatable Bond
5
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00495 | N-(2,6-dimethylphenyl)formamide |
|
O=CNc1c(cccc1C)C | 0.0065 |
| FDBF00663 | 1-methylpiperidine |
|
CN1CCCCC1 | 0.0172 |
| FDBF00668 | (2S)-N-(2,6-dimethylphenyl)-1-methyl-piperidine-2-carboxamide |
|
c1(c(cccc1C)C)NC(=O)C2N(CCCC2)C | 0.0010 |
| FDBF00672 | (2S)-1-ethylpiperidine-2-carboxamide |
|
O=C(N)C1N(CCCC1)CC | 0.0007 |
