Responsive image

Common name

1-methylpiperidine

IUPAC name

1-methylpiperidine

SMILES

CN1CCCCC1

Common name

1-methylpiperidine

IUPAC name

1-methylpiperidine

SMILES

CN1CCCCC1

INCHI

InChI=1S/C6H13N/c1-7-5-3-2-4-6-7/h2-6H2,1H3

FORMULA

C6H13N

Responsive image

Common name

1-methylpiperidine

IUPAC name

1-methylpiperidine





Molecular weight

99.174

clogP

1.483

clogS

-0.911

Frequency

0.0172





HBond Acceptor

1

HBond Donor

0

Total Polar
Surface Area

3.24

Number of Rings

1

Rotatable Bond

0

Drug ID Common name Structure CAS Compound class Therapeutic area
FDBD00183 Ropivacaine Responsive image Anesthetics, Local; Anesthetics; Nervous System; Amides; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Used in obstetric anesthesia and regional anesthesia for surgery.
FDBD00184 Bupivacaine Responsive image Anesthetics, Local; Anesthetics; Nervous System; Amides; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C19 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; For the production of local or regional anesthesia or analgesia for surgery, for oral surgery procedures, for diagnostic and therapeutic procedures, and for obstetrical procedures.
FDBD00225 Metixene Responsive image Nervous System; Anti-Parkinson Drugs; Anticholinergics; Tertiary Amines; Used for the symptomatic treatment of parkinsonism.
FDBD00258 Trihexyphenidyl Responsive image Antiparkinson Agents; Muscarinic Antagonists; Antidyskinetics; Nervous System; Anti-Parkinson Drugs; Anticholinergics; Tertiary Amines; Indicated for the treatment of parkinson's disease and extrapyramidal reactions caused by drugs.
FDBD00329 Pethidine Responsive image Analgesics; Analgesics, Opioid; Narcotics; Adjuvants, Anesthesia; Adjuvants; Nervous System; Opioids; Phenylpiperidine Derivatives; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Used to control moderate to severe pain.
FDBD00354 Raloxifene Responsive image Bone Density Conservation Agents; Estrogen Antagonists; Selective Estrogen Receptor Modulators; Antihypocalcemic Agents; Sex Hormones and Modulators of the Genital System; Genito Urinary System and Sex Hormones; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP3A4 Inhibitors; For the prevention and treatment of osteoporosis in post-menopausal women, as well as prevention and treatment of corticosteroid-induced bone loss. Also for the reduction in the incidence of invasive breast cancer in postmenopausal women with osteoporosis or have a high risk for developing breast cancer.
FDBD00469 Cisapride Responsive image Gastrointestinal Agents; Anti-Ulcer Agents; Serotonin Receptor Agonists; Prokinetic Agents; Alimentary Tract and Metabolism; Drugs for Functional Gastrointestinal Disorders; Propulsives; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2A6 Inhibitors; CYP2A6 Inhibitors (strong); CYP2A6 Inhibitors (moderate); CYP2A6 Inducers; CYP2A6 Inducers (strong); CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
FDBD00502 Astemizole Responsive image Anti-Allergic Agents; Histamine H1 Antagonists, Non-Sedating; Histamine Antagonists; Respiratory System; Antihistamines for Systemic Use; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Combined Inhibitors of CYP3A4 and P-glycoprotein; Astemizole was indicated for use in the relieving allergy symptoms, particularly rhinitis and conjunctivitis. It has been withdrawn from the market however due to concerns of arrhythmias.
FDBD00510 Dyclonine Responsive image Anesthetics, Local; Anesthetics; Respiratory System; Throat Preparations; Nervous System; Used to provide topical anesthesia of accessible mucous membranes prior to examination, endoscopy or instrumentation, or other procedures involving the esophagus, larynx, mouth, pharynx or throat, respiratory tract or trachea, urinary tract, or vagina. Also used to suppress the gag reflex and/or other laryngeal and esophageal reflexes to facilitate dental examination or procedures (including oral surgery), endoscopy, or intubation. Also used for relief of canker sores, cold sores or fever blister.
FDBD00544 Thioridazine Responsive image Antipsychotic Agents; Adrenergic alpha-1 Receptor Antagonists; Dopamine Antagonists; Phenothiazines; Nervous System; Psycholeptics; Phenothiazines With Piperidine Structure; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); For the treatment of schizophrenia and generalized anxiety disorder.
50 , 6
FRAGNAME PDBID SIMILIRITY XSCORE SMILE HAC
2bys_ligand_frag_3.mol2 2bys 1 -6.50 C1CCCC[NH+]1C 7
2iog_ligand_1_10.mol2 2iog 1 -6.37 [NH+]1(CCCCC1)C 7
3m8q_ligand_1_4.mol2 3m8q 1 -6.30 C[NH+]1CCCCC1 7
1o79_ligand_1_0.mol2 1o79 1 -6.29 C1CC[NH+](CC1)C 7
1eve_ligand_1_4.mol2 1eve 1 -6.25 C[NH+]1CCCCC1 7
3i6m_ligand_1_4.mol2 3i6m 1 -6.20 [NH+]1(CCCCC1)C 7
4li8_ligand_1_4.mol2 4li8 1 -6.20 [NH+]1(CCCCC1)C 7
2y1w_ligand_1_2.mol2 2y1w 1 -6.18 C[NH+]1CCCCC1 7
123 , 13