Responsive image

Common name


Valproic Acid

IUPAC name


2-propylpentanoic acid

SMILES


CCCC(CCC)C(O)=O

Compound class


Enzyme Inhibitors; Anticonvulsants; Antimanic Agents; GABA Agents; Nervous System; Antiepileptics; Fatty Acid Derivatives; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2A6 Inhibitors; CYP2A6 Inhibitors (strong); CYP2A6 Inhibitors (moderate); CYP2A6 Inducers; CYP2A6 Inducers (strong); CYP2B6 Inhibitors (strong); CYP3A4 Inhibitors;

Therapeutic area


For treatment and management of seizure disorders, mania, and prophylactic treatment of migraine headache. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, and the seizures associated with Lennox-Gastaut syndrome.

Common name


Valproic Acid

IUPAC name


2-propylpentanoic acid

SMILES


CCCC(CCC)C(O)=O

INCHI


InChI=1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)

FORMULA


C8H16O2

Responsive image

Common name


Valproic Acid

IUPAC name


2-propylpentanoic acid

Molecular weight


144.211

clogP


1.600

clogS


-1.672

HBond Acceptor


2

HBond Donor


1

Total Polar
Surface Area


37.3

Number of Rings


0

Rotatable Bond


5

Drug ID Common name Structure CAS SMILE Frequency
FDBF00004 acetic acid Responsive image CC(=O)O 0.0687
FDBF00007 propane Responsive image C(C)C 0.2412
FDBF00047 propionic acid Responsive image CCC(=O)O 0.0395
FDBF00062 pentanoic acid Responsive image CCCCC(=O)O 0.0079
FDBF00240 2-methylpropanoic acid Responsive image CC(C)C(=O)O 0.0027
FDBF00699 (2S)-2-methylpentanoic acid Responsive image C(C)CC(C)C(=O)O 0.0007
FDBF00700 (2R)-2-methylpentanoic acid Responsive image C(C)CC(C)C(=O)O 0.0007
7 , 1