Responsive image

Common name


Methylphenidate

IUPAC name


methyl 2-phenyl-2-(piperidin-2-yl)acetate

SMILES


COC(=O)C(C1CCCCN1)C1=CC=CC=C1

Compound class


Central Nervous System Stimulants; Dopamine Uptake Inhibitors; Nervous System; Psychoanaleptics; Centrally Acting Sympathomimetics; Psychostimulants, Agents Used for Adhd and Nootropics; CYP2D6 Inducers; CYP2D6 Inducers (strong);

Therapeutic area


For use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate-to-severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.

Common name


Methylphenidate

IUPAC name


methyl 2-phenyl-2-(piperidin-2-yl)acetate

SMILES


COC(=O)C(C1CCCCN1)C1=CC=CC=C1

INCHI


InChI=1S/C14H19NO2/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3

FORMULA


C14H19NO2

Responsive image

Common name


Methylphenidate

IUPAC name


methyl 2-phenyl-2-(piperidin-2-yl)acetate

Molecular weight


233.306

clogP


2.633

clogS


-2.982

HBond Acceptor


2

HBond Donor


1

Total Polar
Surface Area


38.33

Number of Rings


2

Rotatable Bond


4

Drug ID Common name Structure CAS SMILE Frequency
FDBF00005 benzene Responsive image c1ccccc1 0.2824
FDBF00023 toluene Responsive image c1(ccccc1)C 0.1268
FDBF00101 methyl acetate Responsive image O(C(=O)C)C 0.0151
FDBF00105 methyl formate Responsive image O(C=O)C 0.0323
FDBF00670 piperidine Responsive image N1CCCCC1 0.0199
FDBF00916 (2R)-2-methylpiperidine Responsive image CC1NCCCC1 0.0003
FDBF00917 methyl 2-[(2S)-2-piperidyl]acetate Responsive image C(C(=O)OC)C1NCCCC1 0.0003
FDBF00918 methyl 2-phenylacetate Responsive image C(c1ccccc1)C(=O)OC 0.0010
8 , 1