IUPAC name
3-methyl-3-nitroso-1-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
SMILES
CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
Compound class
Antineoplastic Agents; Immunosuppressive Agents; Antibiotics, Antineoplastic; Alkylating Agents; Antibiotics; Antineoplastic and Immunomodulating Agents; Nitrosoureas; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong);
Therapeutic area
For the treatment of malignant neoplasms of pancreas (metastatic islet cell carcinoma).
Common name
Streptozocin
IUPAC name
3-methyl-3-nitroso-1-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
SMILES
CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
INCHI
InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1
FORMULA
C8H15N3O7
Common name
Streptozocin
IUPAC name
3-methyl-3-nitroso-1-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
Molecular weight
265.221
clogP
-3.467
clogS
2.360
HBond Acceptor
8
HBond Donor
5
Total Polar Surface Area
151.92
Number of Rings
1
Rotatable Bond
4
