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Common name


Cinchocaine

IUPAC name


2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide

SMILES


CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC

Compound class


Anesthetics, Local; Anesthetics; Ophthalmologicals; Sensory Organs; Dermatologicals; Nervous System; Cardiovascular System; Local Anesthetics; Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use; Vasoprotectives; Anesthetics for Topical Use; Antipruritics, Incl. Antihistamines, Anesthetics, Etc.; Amides; Analgesics and Anesthetics; Otologicals;

Therapeutic area


For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.

Common name


Cinchocaine

IUPAC name


2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide

SMILES


CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC

INCHI


InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24)

FORMULA


C20H29N3O2

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Common name


Cinchocaine

IUPAC name


2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide

Molecular weight


343.463

clogP


3.890

clogS


-5.981

HBond Acceptor


4

HBond Donor


1

Total Polar
Surface Area


54.46

Number of Rings


2

Rotatable Bond


10

Drug ID Common name Structure CAS SMILE Frequency
FDBF00003 formamide Responsive image C(=O)N 0.1240
FDBF00007 propane Responsive image C(C)C 0.2412
FDBF00040 ethanamine Responsive image CCN 0.0677
FDBF00041 ethanol Responsive image CCO 0.1474
FDBF00789 quinoline Responsive image n1c2c(ccc1)cccc2 0.0041
FDBF01185 1H-quinolin-2-one Responsive image [nH]1c2c(ccc1=O)cccc2 0.0007
FDBF01186 quinoline-4-carboxamide Responsive image n1c2c(c(cc1)C(=O)N)cccc2 0.0003
FDBF01188 N-methylquinoline-4-carboxamide Responsive image CNC(=O)c1c2c(ncc1)cccc2 0.0003
FDBF01190 2-ethoxyquinoline Responsive image O(c1nc2c(cc1)cccc2)CC 0.0003
FDBF01193 N-ethyl-2-methoxy-quinoline-4-carboxamide Responsive image COc1nc2c(c(c1)C(=O)NCC)cccc2 0.0003
21 , 3