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Common name


Cinchocaine

IUPAC name


2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide

SMILES


CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC

Compound class


Anesthetics, Local; Anesthetics; Ophthalmologicals; Sensory Organs; Dermatologicals; Nervous System; Cardiovascular System; Local Anesthetics; Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use; Vasoprotectives; Anesthetics for Topical Use; Antipruritics, Incl. Antihistamines, Anesthetics, Etc.; Amides; Analgesics and Anesthetics; Otologicals;

Therapeutic area


For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.

Common name


Cinchocaine

IUPAC name


2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide

SMILES


CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC

INCHI


InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24)

FORMULA


C20H29N3O2

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Common name


Cinchocaine

IUPAC name


2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide

Molecular weight


343.463

clogP


3.890

clogS


-5.981

HBond Acceptor


4

HBond Donor


1

Total Polar
Surface Area


54.46

Number of Rings


2

Rotatable Bond


10

Drug ID Common name Structure CAS SMILE Frequency
FDBF00067 butane Responsive image CCCC 0.0680
FDBF00068 N-methylethanamine Responsive image N(CC)C 0.0429
FDBF00070 N-ethylethanamine Responsive image N(CC)CC 0.0240
FDBF00294 N-ethyl-N-methyl-ethanamine Responsive image C(C)N(CC)C 0.0134
FDBF00416 butan-1-ol Responsive image C(CC)CO 0.0134
FDBF00696 N,N-diethylethanamine Responsive image C(C)N(CC)CC 0.0079
FDBF01187 2-methoxyquinoline Responsive image n1c2c(ccc1OC)cccc2 0.0003
FDBF01189 N-ethylquinoline-4-carboxamide Responsive image CCNC(=O)c1c2c(ncc1)cccc2 0.0003
FDBF01192 2-methoxy-N-methyl-quinoline-4-carboxamide Responsive image COc1nc2c(c(c1)C(=O)NC)cccc2 0.0003
FDBF01194 2-ethoxy-N-methyl-quinoline-4-carboxamide Responsive image CCOc1nc2c(c(c1)C(=O)NC)cccc2 0.0003
21 , 3