Responsive image

Common name


Carbinoxamine

IUPAC name


{2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine

SMILES


CN(C)CCOC(C1=CC=C(Cl)C=C1)C1=CC=CC=N1

Compound class


Histamine H1 Antagonists; Histamine Antagonists; Respiratory System; Aminoalkyl Ethers; Antihistamines for Systemic Use; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors;

Therapeutic area


For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis, as well as allergic conjunctivitis caused by foods and inhaled allergens. Also for the relief of allergic reactions to blood or plasma, and the symptomatic management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema.

Common name


Carbinoxamine

IUPAC name


{2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine

SMILES


CN(C)CCOC(C1=CC=C(Cl)C=C1)C1=CC=CC=N1

INCHI


InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3

FORMULA


C16H19ClN2O

Responsive image

Common name


Carbinoxamine

IUPAC name


{2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine

Molecular weight


290.788

clogP


3.536

clogS


-4.650

HBond Acceptor


3

HBond Donor


0

Total Polar
Surface Area


25.36

Number of Rings


2

Rotatable Bond


6

Drug ID Common name Structure CAS SMILE Frequency
FDBF00016 chlorobenzene Responsive image c1ccc(cc1)Cl 0.0718
FDBF00041 ethanol Responsive image CCO 0.1474
FDBF00064 N,N-dimethylmethanamine Responsive image N(C)(C)C 0.0371
FDBF00289 N,N-dimethylethanamine Responsive image C(C)N(C)C 0.0299
FDBF00292 2-(dimethylamino)ethanol Responsive image CN(CCO)C 0.0045
FDBF00361 2-methylpyridine Responsive image n1c(cccc1)C 0.0058
FDBF01726 2-pyridylmethanol Responsive image n1c(cccc1)CO 0.0010
FDBF01727 1-chloro-4-(methoxymethyl)benzene Responsive image O(C)Cc1ccc(cc1)Cl 0.0014
FDBF01728 2-(methoxymethyl)pyridine Responsive image n1c(cccc1)COC 0.0007
FDBF01729 2-methoxy-N,N-dimethyl-ethanamine Responsive image N(C)(C)CCOC 0.0017
17 , 2