IUPAC name
6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ
SMILES
NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl
Compound class
Antihypertensive Agents; Diuretics; Sodium Chloride Symporter Inhibitors; Cardiovascular System; Thiazides, Plain; Low-Ceiling Diuretics, Thiazides; Low-Ceiling Diuretics and Potassium-Sparing Agents;
Therapeutic area
Used in the treatment of oedema (including that associated with heart failure) and hypertension.
Common name
Trichlormethiazide
IUPAC name
6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ
SMILES
NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl
INCHI
InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
FORMULA
C8H8Cl3N3O4S2
Common name
Trichlormethiazide
IUPAC name
6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ
Molecular weight
380.656
clogP
-0.030
clogS
-3.566
HBond Acceptor
4
HBond Donor
4
Total Polar Surface Area
118.36
Number of Rings
2
Rotatable Bond
2
