Common name
dichloromethane
IUPAC name
dichloromethane
SMILES
ClCCl
Common name
dichloromethane
IUPAC name
dichloromethane
SMILES
ClCCl
INCHI
InChI=1S/CH2Cl2/c2-1-3/h1H2
FORMULA
CH2Cl2
Common name
dichloromethane
IUPAC name
dichloromethane
Molecular weight
84.933
clogP
1.697
clogS
-1.408
Frequency
0.0045
HBond Acceptor
0
HBond Donor
0
Total PolarSurface Area
0
Number of Rings
0
Rotatable Bond
0
| Drug ID | Common name | Structure CAS | Compound class | Therapeutic area |
|---|---|---|---|---|
| FDBD00322 | Chloramphenicol |
|
Anti-Bacterial Agents; Protein Synthesis Inhibitors; Anti-Acne Preparations; Antibiotics; Ophthalmologicals; Sensory Organs; Genito Urinary System and Sex Hormones; Antibacterials for Systemic Use; Antiinfectives for Systemic Use; Dermatologicals; Gynecological Antiinfectives and Antiseptics; Anti-Acne Preparations for Topical Use; Antiinfectives; Antiinfectives for Treatment of Acne; Antibacterials for Intramammary Use; Otologicals; Antibiotics for Topical Use; Ophthalmological and Otological Preparations; Amphenicols; Amphenicols for Intramammary Use; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP3A4 Inhibitors; | Used in treatment of cholera, as it destroys the vibrios and decreases the diarrhea. It is effective against tetracycline-resistant vibrios. It is also used in eye drops or ointment to treat bacterial conjunctivitis. |
| FDBD00513 | Mitotane |
|
Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic and Immunomodulating Agents; | For treatment of inoperable adrenocortical tumours; Cushing's syndrome. |
| FDBD00584 | Clodronate |
|
Bone Density Conservation Agents; Antihypocalcemic Agents; Bisphosphonates; | For the management of hypercalcemia of malignancy and as an adjunct in the management of osteolysis resulting from bone metastases of malignant tumors. |
| FDBD00875 | Trichlormethiazide |
|
Antihypertensive Agents; Diuretics; Sodium Chloride Symporter Inhibitors; Cardiovascular System; Thiazides, Plain; Low-Ceiling Diuretics, Thiazides; Low-Ceiling Diuretics and Potassium-Sparing Agents; | Used in the treatment of oedema (including that associated with heart failure) and hypertension. |
| FDBD00881 | Methoxyflurane |
|
Anesthetics, Inhalation; Analgesics; Nervous System; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2A6 Inhibitors; CYP2A6 Inhibitors (strong); CYP2A6 Inhibitors (moderate); CYP2A6 Inducers; CYP2A6 Inducers (strong); CYP2B6 Inhibitors (strong); CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors; | For use in the induction and maintenance of general anesthesia. |
| FDBD01417 | Cangrelor |
|
Platelet Aggregation Inhibitors; Antithrombotic Agents; Blood and Blood Forming Organs; Platelet Aggregation Inhibitors Excl. Heparin; Purinergic P2Y Receptor Antagonists; | For use as an adjunct to percutaneous coronary intervention (PCI) for reducing the risk of periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST) in patients in who have not been treated with a P2Y12 platelet inhibitor and are not being given a glycoprotein IIb/IIIa inhibitor. |
| FDBD01512 | Diloxanide |
|
Diloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially, with other agents such as the nitroimidazoles (eg. metronidazole) in the treatment of invasive or extraintestinal forms of amebiasis. | |
| FDBD01954 | methylene chloride |
|
Insecticide | Insecticide |
| FDBD01959 | tetrachloroethane |
|
Insecticide | Insecticide |
| FDBD02037 | ethyl-DDD |
|
Insecticide | Insecticide |
13 ,
2
| FRAGNAME | PDBID | SIMILIRITY | XSCORE | SMILE | HAC |
|---|---|---|---|---|---|
| 4yas_ligand_frag_0.mol2 | 4yas | 1 | -5.97 | C(Cl)(Cl)Cl | 4 |
| 4mgd_ligand_frag_2.mol2 | 4mgd | 1 | -5.90 | C(Cl)(Cl)Cl | 4 |
| 4zow_ligand_frag_0.mol2 | 4zow | 1 | -5.50 | C(Cl)Cl | 3 |
| 1ct8_ligand_frag_1.mol2 | 1ct8 | 1 | -5.48 | ClCCl | 3 |
| 4djo_ligand_frag_15.mol2 | 4djo | 1 | -5.34 | C(Cl)Cl | 3 |
| 4mgd_ligand_1_1.mol2 | 4mgd | 0.6 | -6.25 | CC(Cl)(Cl)Cl | 5 |
| 4o2p_ligand_1_7.mol2 | 4o2p | 0.4 | -5.63 | C(Cl)C | 3 |
| 5cqj_ligand_frag_1.mol2 | 5cqj | 0.4 | -5.44 | CCCl | 3 |
| 3f78_ligand_1_1.mol2 | 3f78 | 0.4 | -5.42 | OCCl | 3 |
| 1xa5_ligand_1_4.mol2 | 1xa5 | 0.4 | -5.33 | C(Cl)C | 3 |
640 ,
65
