IUPAC name
4-(2,2-dichloro-N-methylacetamido)phenyl furan-2-carboxylate
SMILES
CN(C(=O)C(Cl)Cl)C1=CC=C(OC(=O)C2=CC=CO2)C=C1
Compound class
Therapeutic area
Diloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially, with other agents such as the nitroimidazoles (eg. metronidazole) in the treatment of invasive or extraintestinal forms of amebiasis.
Common name
Diloxanide
IUPAC name
4-(2,2-dichloro-N-methylacetamido)phenyl furan-2-carboxylate
SMILES
CN(C(=O)C(Cl)Cl)C1=CC=C(OC(=O)C2=CC=CO2)C=C1
INCHI
InChI=1S/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3
FORMULA
C14H11Cl2NO4
Common name
Diloxanide
IUPAC name
4-(2,2-dichloro-N-methylacetamido)phenyl furan-2-carboxylate
Molecular weight
328.147
clogP
2.701
clogS
-3.685
HBond Acceptor
4
HBond Donor
0
Total Polar Surface Area
59.75
Number of Rings
2
Rotatable Bond
6
