
IUPAC name
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
SMILES
OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)C1=CC=C(C=C1)[N+]([O-])=O
Compound class
Anti-Bacterial Agents; Protein Synthesis Inhibitors; Anti-Acne Preparations; Antibiotics; Ophthalmologicals; Sensory Organs; Genito Urinary System and Sex Hormones; Antibacterials for Systemic Use; Antiinfectives for Systemic Use; Dermatologicals; Gynecological Antiinfectives and Antiseptics; Anti-Acne Preparations for Topical Use; Antiinfectives; Antiinfectives for Treatment of Acne; Antibacterials for Intramammary Use; Otologicals; Antibiotics for Topical Use; Ophthalmological and Otological Preparations; Amphenicols; Amphenicols for Intramammary Use; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP3A4 Inhibitors;
Therapeutic area
Used in treatment of cholera, as it destroys the vibrios and decreases the diarrhea. It is effective against tetracycline-resistant vibrios. It is also used in eye drops or ointment to treat bacterial conjunctivitis.
Common name
Chloramphenicol
IUPAC name
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
SMILES
OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)C1=CC=C(C=C1)[N+]([O-])=O
INCHI
InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1
FORMULA
C11H12Cl2N2O5

Common name
Chloramphenicol
IUPAC name
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
Molecular weight
323.129
clogP
0.841
clogS
-2.410
HBond Acceptor
5
HBond Donor
3
Total Polar Surface Area
121.37
Number of Rings
1
Rotatable Bond
6
Drug ID | Common name | Structure CAS | SMILE | Frequency |
---|---|---|---|---|
FDBF00003 | formamide |
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C(=O)N | 0.1240 |
FDBF00041 | ethanol |
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CCO | 0.1474 |
FDBF00043 | N-(2-hydroxyethyl)formamide |
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C(CO)NC=O | 0.0065 |
FDBF00151 | propane-1,3-diol |
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C(O)CCO | 0.0045 |
FDBF00779 | nitrobenzene |
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O=N(=O)c1ccccc1 | 0.0134 |
FDBF00968 | 2,2-dichloroacetamide |
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ClC(Cl)C(=O)N | 0.0003 |
FDBF00969 | 2,2-dichloro-N-methyl-acetamide |
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ClC(Cl)C(=O)NC | 0.0007 |
FDBF00970 | 2,2-dichloro-N-(2-hydroxyethyl)acetamide |
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C(O)CNC(=O)C(Cl)Cl | 0.0003 |
FDBF00971 | dichloromethane |
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ClCCl | 0.0045 |