IUPAC name
N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide
SMILES
CC1=CC(=NO1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CCCCCC1
Compound class
Drugs Used in Diabetes; Alimentary Tract and Metabolism; Blood Glucose Lowering Drugs, Excl. Insulins; Sulfonylureas;
Therapeutic area
For the treatment of diabetes mellitus type 2.
Common name
Glisoxepide
IUPAC name
N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide
SMILES
CC1=CC(=NO1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CCCCCC1
INCHI
InChI=1S/C20H27N5O5S/c1-15-14-18(23-30-15)19(26)21-11-10-16-6-8-17(9-7-16)31(28,29)24-20(27)22-25-12-4-2-3-5-13-25/h6-9,14H,2-5,10-13H2,1H3,(H,21,26)(H2,22,24,27)
FORMULA
C20H27N5O5S
Common name
Glisoxepide
IUPAC name
N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide
Molecular weight
449.524
clogP
0.740
clogS
-5.053
HBond Acceptor
7
HBond Donor
3
Total Polar Surface Area
133.64
Number of Rings
3
Rotatable Bond
7
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00003 | formamide |
|
C(=O)N | 0.1240 |
| FDBF00005 | benzene |
|
c1ccccc1 | 0.2824 |
| FDBF00023 | toluene |
|
c1(ccccc1)C | 0.1268 |
| FDBF00141 | ethylbenzene |
|
c1(ccccc1)CC | 0.0371 |
| FDBF00143 | N-phenethylformamide |
|
c1(ccccc1)CCNC=O | 0.0041 |
| FDBF00686 | 5-methylisoxazole |
|
o1nccc1C | 0.0031 |
| FDBF01888 | azepane |
|
N1CCCCCC1 | 0.0014 |
| FDBF02908 | N,5-dimethylisoxazole-3-carboxamide |
|
o1nc(cc1C)C(=O)NC | 0.0003 |
| FDBF02909 | N-ethyl-5-methyl-isoxazole-3-carboxamide |
|
o1nc(cc1C)C(=O)NCC | 0.0003 |
