IUPAC name
(1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine
SMILES
C#CCN[C@@H]1CCC2=CC=CC=C12
Compound class
Neuroprotective Agents; Monoamine Oxidase Inhibitors; Nervous System; Anti-Parkinson Drugs; Dopaminergic Agents; Monoamine Oxidase B Inhibitors; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers;
Therapeutic area
For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
Common name
Rasagiline
IUPAC name
(1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine
SMILES
C#CCN[C@@H]1CCC2=CC=CC=C12
INCHI
InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1
FORMULA
C12H13N
Common name
Rasagiline
IUPAC name
(1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine
Molecular weight
171.238
clogP
2.847
clogS
-2.925
HBond Acceptor
0
HBond Donor
1
Total Polar Surface Area
12.03
Number of Rings
2
Rotatable Bond
3
