Responsive image

Common name


Debrisoquin

IUPAC name


1,2,3,4-tetrahydroisoquinoline-2-carboximidamide

SMILES


NC(=N)N1CCC2=CC=CC=C2C1

Compound class


Antihypertensive Agents; Adrenergic Agents; Sympatholytics; Cardiovascular System; Guanidine Derivatives; Antiadrenergic Agents, Peripherally Acting; CYP2D6 Inducers; CYP2D6 Inducers (strong);

Therapeutic area


For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.

Common name


Debrisoquin

IUPAC name


1,2,3,4-tetrahydroisoquinoline-2-carboximidamide

SMILES


NC(=N)N1CCC2=CC=CC=C2C1

INCHI


InChI=1S/C10H13N3/c11-10(12)13-6-5-8-3-1-2-4-9(8)7-13/h1-4H,5-7H2,(H3,11,12)

FORMULA


C10H13N3

Responsive image

Common name


Debrisoquin

IUPAC name


1,2,3,4-tetrahydroisoquinoline-2-carboximidamide

Molecular weight


175.230

clogP


1.084

clogS


-1.689

HBond Acceptor


1

HBond Donor


3

Total Polar
Surface Area


53.11

Number of Rings


2

Rotatable Bond


1

Drug ID Common name Structure CAS SMILE Frequency
FDBF00001 methanimidamide Responsive image N=CN 0.0062
FDBF03181 1,2,3,4-tetrahydroisoquinoline Responsive image N1CCc2c(cccc2)C1 0.0003
2 , 1