Common name
methanimidamide
IUPAC name
methanimidamide
SMILES
N=CN
Common name
methanimidamide
IUPAC name
methanimidamide
SMILES
N=CN
INCHI
InChI=1S/CH4N2/c2-1-3/h1H,(H3,2,3)
FORMULA
CH4N2
Common name
methanimidamide
IUPAC name
methanimidamide
Molecular weight
44.056
clogP
-0.344
clogS
0.621
Frequency
0.0062
HBond Acceptor
0
HBond Donor
3
Total PolarSurface Area
49.87
Number of Rings
0
Rotatable Bond
0
| Drug ID | Common name | Structure CAS | Compound class | Therapeutic area |
|---|---|---|---|---|
| FDBD00001 | Bivalirudin |
|
Antithrombins; Direct Thrombin Inhibitors; Antithrombotic Agents; Blood and Blood Forming Organs; | For treatment of heparin-induced thrombocytopenia and for the prevention of thrombosis. |
| FDBD00003 | Desmopressin |
|
Antidiuretic Agents; Hemostatics; Renal Agents; Pituitary and Hypothalamic Hormones and Analogues; Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins; Vasopressin and Analogues; Posterior Pituitary Lobe Hormones; | Oral formulations may be used to manage primary nocturnal enuresis in adults and vasopressin sensitive diabetes insipidus, and for control of temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. Intranasal and parenteral formulations may be used to manage spontaneous or trauma-induced bleeds (e.g. hemarthrosis, intramuscular hematoma, mucosal bleeding) in patients with hemophilia A or von Willebrand's disease Type I. May also be used parenterally to prevent or treat bleeding in patients with uremia. |
| FDBD00004 | Cetrorelix |
|
Fertility Agents, Female; Hormone Antagonists; Fertility Agents; Pituitary and Hypothalamic Hormones and Analogues; Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins; Anti-Gonadotropin-Releasing Hormones; Hypothalamic Hormones; | For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. |
| FDBD00039 | Creatine |
|
Dietary Supplements; Micronutrients; Supplements; | For nutritional supplementation, also for treating dietary shortage or imbalance. |
| FDBD00531 | Nafarelin |
|
Fertility Agents, Female; Antiendometriotic agent; Gonadotropin-releasing hormone agonist; Pituitary and Hypothalamic Hormones and Analogues; Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins; Hypothalamic Hormones; Gonadotropin-Releasing Hormones; | For treatment of central precocious puberty (true precocious puberty, GnRH-dependent precocious precocity, complete isosexual precocity) in children of both sexes and for the treatment of endometriosis. |
| FDBD00602 | Pentamidine |
|
Antifungal Agents; Antiprotozoal Agents; Trypanocidal Agents; Antiparasitic Products, Insecticides and Repellents; Agents Against Protozoal Diseases; Agents Against Leishmaniasis and Trypanosomiasis; Aromatic Diamidines; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; | For the treatment of pneumonia due to . |
| FDBD01248 | Imipenem |
|
Anti-Bacterial Agents; Antibacterials for Systemic Use; Antiinfectives for Systemic Use; Carbapenems; | For the treatment of bacterial infections caused by susceptible bacteria. |
| FDBD01325 | Debrisoquin |
|
Antihypertensive Agents; Adrenergic Agents; Sympatholytics; Cardiovascular System; Guanidine Derivatives; Antiadrenergic Agents, Peripherally Acting; CYP2D6 Inducers; CYP2D6 Inducers (strong); | For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension. |
| FDBD01484 | Histrelin |
|
Histrelin acetate has two indications | |
| FDBD01507 | Triptorelin |
|
Antineoplastic Agents, Hormonal; Luteolytic Agents; Antineoplastic and Immunomodulating Agents; Gonadotropin Releasing Hormone Analogues; Hormones and Related Agents; Endocrine Therapy; Pituitary and Hypothalamic Hormones and Analogues; Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins; Hypothalamic Hormones; Gonadotropin-Releasing Hormones; | Triptorelin is indicated for the palliative treatment of advanced prostate cancer. |
18 ,
2
| FRAGNAME | PDBID | SIMILIRITY | XSCORE | SMILE | HAC |
|---|---|---|---|---|---|
| 1c5t_ligand_frag_0.mol2 | 1c5t | 1 | -5.52 | C(=N)N | 3 |
| 1c5y_ligand_frag_0.mol2 | 1c5y | 1 | -5.49 | C(=N)N | 3 |
| 1c5s_ligand_frag_0.mol2 | 1c5s | 1 | -5.46 | C(=N)N | 3 |
| 1qhr_ligand_frag_4.mol2 | 1qhr | 1 | -5.43 | C(=N)N | 3 |
| 1c5n_ligand_frag_0.mol2 | 1c5n | 1 | -5.36 | C(=N)N | 3 |
| 1c4u_ligand_frag_8.mol2 | 1c4u | 1 | -5.35 | C(=N)N | 3 |
| 1o0d_ligand_frag_0.mol2 | 1o0d | 1 | -5.32 | NC=N | 3 |
| 4uiw_ligand_frag_4.mol2 | 4uiw | 1 | -5.22 | C(=N)N | 3 |
| 4oth_ligand_frag_0.mol2 | 4oth | 1 | -5.13 | C(=N)N | 3 |
999 ,
100
