
IUPAC name
{[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methoxy}phosphonic acid
SMILES
CN1N=NC(=N1)C1=CC=C(C=N1)C1=CC=C(C=C1F)N1C[C@H](COP(O)(O)=O)OC1=O
Compound class
Anti-Bacterial Agents; Antibacterials for Systemic Use; Antiinfectives for Systemic Use;
Therapeutic area
Tedizolid Phosphate is an oxazolidinone antibacterial drug indicated in adults for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible isolates of the following Gram-positive microorganisms: Staphylococcus aureus (including methicillin-resistant [MRSA] and methicillin-susceptible [MSSA] isolates), Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus anginosus Group (including Streptococcus anginosus, Streptococcus intermedius, and Streptococcus constellatus), and Enterococcus faecalis.
Common name
Tedizolid Phosphate
IUPAC name
{[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methoxy}phosphonic acid
SMILES
CN1N=NC(=N1)C1=CC=C(C=N1)C1=CC=C(C=C1F)N1C[C@H](COP(O)(O)=O)OC1=O
INCHI
InChI=1S/C17H16FN6O6P/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(30-17(24)25)9-29-31(26,27)28/h2-7,12H,8-9H2,1H3,(H2,26,27,28)/t12-/m1/s1
FORMULA
C17H16FN6O6P

Common name
Tedizolid Phosphate
IUPAC name
{[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methoxy}phosphonic acid
Molecular weight
450.318
clogP
-0.134
clogS
-2.539
HBond Acceptor
10
HBond Donor
2
Total Polar
Surface Area
152.79
Number of Rings
4
Rotatable Bond
6
Drug ID | Common name | Structure CAS | SMILE | Frequency |
---|---|---|---|---|
FDBF00014 | pyridine |
![]() |
c1cccnc1 | 0.0333 |
FDBF00378 | fluorobenzene |
![]() |
Fc1ccccc1 | 0.0237 |
FDBF00707 | oxazolidin-2-one |
![]() |
O1CCNC1=O | 0.0024 |
FDBF01339 | 3-(3-fluorophenyl)oxazolidin-2-one |
![]() |
O1CCN(C1=O)c2cccc(c2)F | 0.0007 |
FDBF01341 | (5S)-5-methyloxazolidin-2-one |
![]() |
CC1OC(=O)NC1 | 0.0014 |
FDBF01342 | (5S)-3-(3-fluorophenyl)-5-methyl-oxazolidin-2-one |
![]() |
CC1OC(=O)N(C1)c2cccc(c2)F | 0.0007 |
FDBF04010 | 3-[3-fluoro-4-(3-pyridyl)phenyl]oxazolidin-2-one |
![]() |
Fc1cc(ccc1c2cnccc2)N3CCOC3=O | 0.0003 |
FDBF04011 | (5S)-3-[3-fluoro-4-(3-pyridyl)phenyl]-5-methyl-oxazolidin-2-one |
![]() |
Fc1cc(ccc1c2cnccc2)N3CC(OC3=O)C | 0.0003 |
FDBF04012 | 2-methyltetrazole |
![]() |
n1n(nnc1)C | 0.0010 |