| ID LINK | NAME | STRUCTURE CAS | CLOGP | CLOGS | MW | FREQ | DURGS WITH THIS FRAGMENT |
|---|---|---|---|---|---|---|---|
| FDBF00774 | tetrahydrofuran |
|
1.869 | -0.590 | 72.106 | 0.0069 |
Alfuzosin ,Sucralfate ,Zidovudine ,Amprenavir ,Didanosine ,Zalcitabine ,Terazosin ,Posaconazole ,Fosamprenavir ,Afatinib , ( Total
14 Medicines )
dinotefuran ,tefuryltrione ,bromobonil ,furyloxyfen ,furconazole , ( Total 6 Pesticides) |
| FDBF02914 | m-cresol |
|
1.874 | -1.538 | 108.138 | 0.0069 |
Bevantolol ,Thymol ,Apremilast ,Tapentadol ,Tymazoline ,Roxatidine acetate ,Aliskiren , ( Total
7 Medicines )
fenthion ,fenthion-ethyl ,mesulfenfos ,permethrin ,biopermethrin ,transpermethrin ,phenothrin ,valerate ,etofenprox ,flufenprox , ( Total 13 Pesticides) |
| FDBF03150 | (2S)-2-hydroxypropanoic acid |
|
-0.803 | 0.983 | 90.078 | 0.0069 |
Lactic Acid ,Ambrisentan ,Ammonium lactate ,Clinofibrate ,Sodium lactate , ( Total
5 Medicines )
thuringiensin ,fenthiaprop ,cloprop ,4-CPP ,dichlorprop ,fenoprop ,mecoprop ,chlorazifop ,clofop ,diclofop , ( Total 15 Pesticides) |
| FDBF04527 | 2-(3-hydroxyphenyl)acetonitrile |
|
1.650 | -1.673 | 133.147 | 0.0069 | acrinathrin ,brofenvalerate ,brofluthrinate ,cycloprothrin ,cyhalothrin ,gamma-cyhalothrin ,lambda-cyhalothrin ,cypermethrin ,alpha-cypermethrin ,theta-cypermethrin , ( Total 20 Pesticides) |
| FDBF00052 | methylsulfanylmethane |
|
0.393 | -0.597 | 62.134 | 0.0072 |
S-Adenosylmethionine ,L-Methionine ,Bleomycin ,Montelukast ,Cimetidine ,Benzthiazide ,Nizatidine ,Ranitidine ,Famotidine ,Pergolide , ( Total
15 Medicines )
thiofanox ,demephion ,demephion-O ,demephion-S ,thiofluoximate ,mecarbinzid , ( Total 6 Pesticides) |
| FDBF00215 | 2-phenoxyethanol |
|
1.540 | -1.586 | 138.164 | 0.0072 |
Esmolol ,Betaxolol ,Ranolazine ,Metoprolol ,Travoprost ,Atenolol ,Methocarbamol ,Bisoprolol ,Alprenolol ,Guaifenesin , ( Total
20 Medicines )
bitertanol , ( Total 1 Pesticides) |
| FDBF00269 | 1,3-difluorobenzene |
|
2.743 | -2.293 | 114.093 | 0.0072 |
Fluconazole ,Voriconazole ,Trovafloxacin ,Diflunisal ,Posaconazole ,Rufinamide ,Vemurafenib ,Dabrafenib ,Dolutegravir ,Efinaconazole , ( Total
10 Medicines )
diflubenzuron ,flucycloxuron ,lufenuron ,penfluron ,diflufenican ,ipfencarbazone ,florasulam ,flumetsulam ,methiozolin ,diflufenzopyr , ( Total 11 Pesticides) |
| FDBF00616 | prop-2-en-1-ol |
|
0.030 | 0.025 | 58.079 | 0.0072 |
Travoprost ,Alprostadil ,Bimatoprost ,Dinoprostone ,Iloprost ,Fluvastatin ,Rosuvastatin ,Dinoprost Tromethamine ,Epoprostenol ,Oxprenolol , ( Total
15 Medicines )
probenazole ,imazalil ,diniconazole ,diniconazole-M ,uniconazole ,uniconazole-P , ( Total 6 Pesticides) |
| FDBF00690 | pyrrolidine |
|
1.550 | -0.899 | 71.121 | 0.0072 |
Ertapenem ,Procyclidine ,Sulpiride ,Remoxipride ,Triprolidine ,Darifenacin ,Rocuronium ,Meropenem ,Almotriptan ,Atorvastatin , ( Total
20 Medicines )
nornicotine , ( Total 1 Pesticides) |
| FDBF00805 | 2-methoxyethanol |
|
-0.225 | -0.113 | 76.094 | 0.0072 |
Cidofovir ,Erlotinib ,Hydroxyzine ,Bisoprolol ,Candoxatril ,Roxithromycin ,Aciclovir ,Dirithromycin ,Ganciclovir ,Quetiapine , ( Total
17 Medicines )
tolpyralate ,cinosulfuron ,bicyclopyrone ,debacarb , ( Total 4 Pesticides) |
5919 ,
592
