| ID LINK | NAME | STRUCTURE CAS | CLOGP | CLOGS | MW | FREQ | DURGS WITH THIS FRAGMENT |
|---|---|---|---|---|---|---|---|
| FDBF00974 | 1,1,1-trifluoroethane |
|
1.416 | -1.043 | 84.040 | 0.0072 |
Lansoprazole ,Halazepam ,Flecainide ,Sevoflurane ,Polythiazide ,Quazepam ,Silodosin ,Cangrelor ,Lomitapide , ( Total
9 Medicines )
acrinathrin ,flufenprox ,afoxolaner ,fluhexafon ,fluralaner ,tembotrione ,trifloxysulfuron ,prosulfuron ,triflusulfuron ,tolprocarb , ( Total 12 Pesticides) |
| FDBF01437 | 4-chlorophenol |
|
2.061 | -1.793 | 128.556 | 0.0072 |
Clofibrate ,Chlorphenesin ,Niclosamide ,Etofibrate , ( Total
4 Medicines )
flufenprox ,sulcofuron ,rafoxanide ,profoxydim ,ethoxyfen ,4-CPA ,4-CPB ,4-CPP ,clofop ,chloroxuron , ( Total 17 Pesticides) |
| FDBF03270 | 1,1-dichloroethylene |
|
1.439 | -1.473 | 96.943 | 0.0072 |
Permethrin , ( Total
1 Medicines )
calvinphos ,dichlorvos ,chlorempenthrin ,cyfluthrin ,cypermethrin ,alpha-cypermethrin ,theta-cypermethrin ,zeta-cypermethrin ,d-fanshiluquebingjuzhi ,chloroprallethrin , ( Total 20 Pesticides) |
| FDBF00049 | N-methylaniline |
|
1.572 | -2.011 | 107.153 | 0.0076 |
Tetrahydrofolic acid ,Folic Acid ,Chlorambucil ,Methotrexate ,Leucovorin ,Melphalan ,Sulfoxone ,Trimetrexate ,Bepridil ,Aprindine , ( Total
17 Medicines )
cambendichlor ,pyribambenz-isopropyl ,pyribambenz-propyl ,methyldymron ,aureofungin , ( Total 5 Pesticides) |
| FDBF00209 | 1-methylpyrrolidine |
|
1.232 | -0.604 | 85.148 | 0.0076 |
Nicotine ,Eletriptan ,Clemastine ,Procyclidine ,Triprolidine ,Darifenacin ,Tolmetin ,Rocuronium ,Methdilazine ,Atorvastatin , ( Total
21 Medicines )
nicotine , ( Total 1 Pesticides) |
| FDBF00241 | 2-methylpropan-2-amine |
|
-0.127 | -0.595 | 73.137 | 0.0076 |
Phentermine ,Timolol ,Carteolol ,Tigecycline ,Terbutaline ,Salbutamol ,Bupropion ,Nadolol ,Levobunolol ,Pirbuterol , ( Total
18 Medicines )
diafenthiuron ,terbuthylazine ,terbumeton ,terbutryn , ( Total 4 Pesticides) |
| FDBF00547 | chloroethane |
|
0.804 | -1.127 | 64.514 | 0.0076 |
Carmustine ,Chlorambucil ,Cyclophosphamide ,Toremifene ,Uracil mustard ,Mechlorethamine ,Phenoxybenzamine ,Melphalan ,Ifosfamide ,Clindamycin , ( Total
14 Medicines )
cloethocarb ,1,2-dichloropropane ,dialifos ,chlorprocarb ,CEPC ,chlornidine ,fluchloralin ,triasulfuron , ( Total 8 Pesticides) |
| FDBF00660 | thiophene |
|
2.854 | -0.950 | 84.140 | 0.0076 |
Raltitrexed ,Teniposide ,Cefalotin ,Duloxetine ,Sufentanil ,Suprofen ,Eprosartan ,Cefoxitin ,Tiotropium ,Stepronin , ( Total
19 Medicines )
triarathene ,thenylchlor ,ethaboxam , ( Total 3 Pesticides) |
| FDBF00062 | pentanoic acid |
|
0.522 | -0.780 | 102.132 | 0.0079 |
Biotin ,Alpha-Linolenic Acid ,Dihomo-gamma-linolenic acid ,Lipoic Acid ,Valproic Acid ,Mupirocin ,Aminocaproic Acid ,Anisotropine Methylbromide ,Azelaic Acid ,Alprostadil , ( Total
20 Medicines )
copper oleate ,pelargonic acid ,pentachlorophenyl laurate , ( Total 3 Pesticides) |
| FDBF00203 | benzene-1,2-diol |
|
0.942 | -0.579 | 110.111 | 0.0079 |
Masoprocol ,Carbidopa ,Isoetarine ,Reboxetine ,Norepinephrine ,Epinephrine ,Tamsulosin ,Dobutamine ,Methyldopa ,Dopamine , ( Total
21 Medicines )
ethoxysulfuron ,phenylmercury derivative of pyrocatechol , ( Total 2 Pesticides) |
5919 ,
592
