Common name
cyclopentane
IUPAC name
cyclopentane
SMILES
C1CCCC1
Common name
cyclopentane
IUPAC name
cyclopentane
SMILES
C1CCCC1
INCHI
InChI=1S/C5H10/c1-2-4-5-3-1/h1-5H2
FORMULA
C5H10
Common name
cyclopentane
IUPAC name
cyclopentane
Molecular weight
70.133
clogP
2.405
clogS
-1.123
Frequency
0.0034
HBond Acceptor
0
HBond Donor
0
Total PolarSurface Area
0
Number of Rings
1
Rotatable Bond
0
| Drug ID | Common name | Structure CAS | Compound class | Therapeutic area |
|---|---|---|---|---|
| FDBD00416 | Zafirlukast |
|
Anti-Asthmatic Agents; Respiratory System; Drugs for Obstructive Airway Diseases; Leukotriene Receptor Antagonists; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors; | For the prophylaxis and chronic treatment of asthma. |
| FDBD00481 | Candoxatril |
|
Prodrugs; | For treatment of hypertension, improve exercise capacity in patients with CHF receiving angiotensin converting enzyme inhibition. |
| FDBD00900 | Abacavir |
|
Anti-HIV Agents; Reverse Transcriptase Inhibitors; Antiinfectives for Systemic Use; Direct Acting Antivirals; Antivirals for Systemic Use; Nucleoside and Nucleotide Reverse Transcriptase Inhibitors; | For the treatment of HIV-1 infection, in combination with other antiretroviral agents. |
| FDBD01047 | Rifapentine |
|
Leprostatic Agents; Antibiotics, Antitubercular; Antibiotics; Antimycobacterials; Antiinfectives for Systemic Use; Drugs for Treatment of Tuberculosis; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; | For the treatment of pulmonary tuberculosis. |
| FDBD01157 | Penbutolol |
|
Antihypertensive Agents; Adrenergic beta-Antagonists; Cardiovascular System; Beta Blocking Agents; Beta Blocking Agents, Non-Selective; | Penbutolol is indicated in the treatment of mild to moderate arterial hypertension. It may be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics.Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity. |
| FDBD01316 | Quinestrol |
|
Estrogens; Hormone Replacement Agents; | Used in hormone replacement therapy, treating symptoms of menopause such as hot flashes. Also used to treat breast and prostate cancer. |
| FDBD01552 | Ruxolitinib |
|
Antineoplastic Agents; Immunosuppressive Agents; Protein Kinase Inhibitors; Antineoplastic and Immunomodulating Agents; CYP3A4 Inhibitors; | Treatment of intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera (post-PV) myelofibrosis and post-essential thrombocythemia (post-ET) myelofibrosis. [Lexicomp] Myeolofibrosis is the proliferation of abnormal bone marrow stem cells which cause fibrosis (the excessive formation of connective tissue). |
| FDBD02247 | cyclethrin |
|
Insecticide | Insecticide |
| FDBD02880 | pentoxazone |
|
Herbicide | Herbicide |
| FDBD03236 | pencycuron |
|
Fungicide | Fungicide |
10 ,
2
| FRAGNAME | PDBID | SIMILIRITY | XSCORE | SMILE | HAC |
|---|---|---|---|---|---|
| 4x0f_ligand_frag_3.mol2 | 4x0f | 1 | -6.62 | C1CCCC1 | 5 |
| 1zz3_ligand_frag_0.mol2 | 1zz3 | 1 | -6.57 | C1CCCC1 | 5 |
| 1os5_ligand_frag_7.mol2 | 1os5 | 1 | -6.54 | C1CCCC1 | 5 |
| 3frz_ligand_frag_3.mol2 | 3frz | 1 | -6.49 | C1CCCC1 | 5 |
| 1g5s_ligand_frag_0.mol2 | 1g5s | 1 | -6.48 | C1CCCC1 | 5 |
| 2hai_ligand_frag_6.mol2 | 2hai | 1 | -6.46 | C1CCCC1 | 5 |
| 1xom_ligand_frag_4.mol2 | 1xom | 1 | -6.42 | C1CCCC1 | 5 |
127 ,
13
