Responsive image

Common name

N-[[(5S)-3-(3-fluorophenyl)-2-oxo-oxazolidin-5-yl]methyl]acetamide

IUPAC name

N-[[(5S)-3-(3-fluorophenyl)-2-oxo-oxazolidin-5-yl]methyl]acetamide

SMILES

C(NC(=O)C)C1OC(=O)N(C1)c2cccc(c2)F

Common name

N-[[(5S)-3-(3-fluorophenyl)-2-oxo-oxazolidin-5-yl]methyl]acetamide

IUPAC name

N-[[(5S)-3-(3-fluorophenyl)-2-oxo-oxazolidin-5-yl]methyl]acetamide

SMILES

C(NC(=O)C)C1OC(=O)N(C1)c2cccc(c2)F

INCHI

InChI=1S/C12H13FN2O3/c1-8(16)14-6-11-7-15(12(17)18-11)10-4-2-3-9(13)5-10/h2-5,11H,6-7H2,1H3,(H,14,16)/t11-/m0/s1

FORMULA

C12H13FN2O3

Responsive image

Common name

N-[[(5S)-3-(3-fluorophenyl)-2-oxo-oxazolidin-5-yl]methyl]acetamide

IUPAC name

N-[[(5S)-3-(3-fluorophenyl)-2-oxo-oxazolidin-5-yl]methyl]acetamide





Molecular weight

252.242

clogP

1.282

clogS

-2.434

Frequency

0.0003





HBond Acceptor

3

HBond Donor

1

Total Polar
Surface Area

58.64

Number of Rings

2

Rotatable Bond

3

Drug ID Common name Structure CAS Compound class Therapeutic area
FDBD00466 Linezolid Responsive image Anti-Bacterial Agents; Protein Synthesis Inhibitors; Antibacterials for Systemic Use; Antiinfectives for Systemic Use; For the treatment of bacterial infections caused by susceptible strains of vancomycin resistant .
1 , 1
FRAGNAME PDBID SIMILIRITY XSCORE SMILE HAC
2q55_ligand_4_0.mol2 2q55 0.79798 -7.12 CCNC(=O)[C@H]1OC(=O)N(C1)c1ccccc1 17
2i0a_ligand_4_220.mol2 2i0a 0.79798 -6.50 N1(C(=O)O[C@@H](C1)C(=O)NCC)c1ccccc1 17
2q54_ligand_4_1353.mol2 2q54 0.79798 -6.48 C(NC(=O)[C@@H]1CN(c2ccccc2)C(=O)O1)C 17
3gi5_ligand_4_165.mol2 3gi5 0.79798 -6.47 C(C)NC(=O)[C@H]1OC(=O)N(c2ccccc2)C1 17
3mxe_ligand_4_480.mol2 3mxe 0.79798 -6.46 CCNC(=O)[C@@H]1CN(c2ccccc2)C(=O)O1 17
2i0d_ligand_4_703.mol2 2i0d 0.79798 -6.43 C(C)NC(=O)[C@H]1OC(=O)N(c2ccccc2)C1 17
3gi4_ligand_4_483.mol2 3gi4 0.79798 -6.42 N(C(=O)[C@H]1OC(=O)N(c2ccccc2)C1)CC 17
3gi6_ligand_4_703.mol2 3gi6 0.79798 -6.40 CCNC(=O)[C@H]1OC(=O)N(c2ccccc2)C1 17
2q55_ligand_3_0.mol2 2q55 0.747475 -6.84 [C@@H]1(OC(=O)N(C1)c1ccccc1)C(=O)NC 16
2i0a_ligand_3_66.mol2 2i0a 0.747475 -6.22 N1(C(=O)O[C@@H](C1)C(=O)NC)c1ccccc1 16
100 , 11