Responsive image

Common name


propanamide

IUPAC name


propanamide

SMILES


CCC(=O)N

Common name


propanamide

IUPAC name


propanamide

SMILES


CCC(=O)N

INCHI


InChI=1S/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5)

FORMULA


C3H7NO

Responsive image

Common name


propanamide

IUPAC name


propanamide





Molecular weight


73.094

clogP


-0.459

clogS


-0.125

Frequency


0.0148





HBond Acceptor


1

HBond Donor


2

Total Polar
Surface Area


43.09

Number of Rings


0

Rotatable Bond


1

Drug ID Common name Structure CAS Compound class Therapeutic area
FDBD00006 Felypressin Responsive image Vasoconstrictor Agents; Renal Agents; For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential.
FDBD00022 L-Glutamine Responsive image Dietary Supplements; Micronutrients; Supplements; Non-Essential Amino Acids; Alimentary Tract and Metabolism; Amino Acids and Derivatives; Used for nutritional supplementation, also for treating dietary shortage or imbalance.
FDBD00034 Glutathione Responsive image Antidotes; Dietary Supplements; Micronutrients; Supplements; For nutritional supplementation, also for treating dietary shortage or imbalance.
FDBD00066 Valsartan Responsive image Antihypertensive Agents; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Lipid Modifying Agents; Cardiovascular System; Angiotensin II Antagonists, Plain; Agents Acting on the Renin-Angiotensin System; Angiotensin II Antagonists and Diuretics; Angiotensin II Antagonists and Calcium Channel Blockers; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Angiotensin II Receptor Antagonists; May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
FDBD00077 Bortezomib Responsive image Antineoplastic Agents; Antineoplastic and Immunomodulating Agents; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; For treatment of multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
FDBD00100 Remikiren Responsive image Cardiovascular System; Agents Acting on the Renin-Angiotensin System; Renin-Inhibitors; For the treatment of hypertension and heart failure.
FDBD00112 Indinavir Responsive image Protease Inhibitors; HIV Protease Inhibitors; Antiinfectives for Systemic Use; Direct Acting Antivirals; Antivirals for Systemic Use; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Combined Inhibitors of CYP3A4 and P-glycoprotein; Indinavir is an antiretroviral drug for the treatment of HIV infection.
FDBD00167 Disopyramide Responsive image Anti-Arrhythmia Agents; Voltage-Gated Sodium Channel Blockers; Cardiovascular System; Antiarrhythmics, Class I and Iii; Cardiac Therapy; Antiarrythmics, Class I and Iii; Antiarrhythmics, Class Ia; CYP3A4 Inhibitors; For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias. It is a Class Ia antiarrhythmic drug.
FDBD00572 Sufentanil Responsive image Anesthetics, Intravenous; Analgesics, Opioid; Narcotics; Adjuvants, Anesthesia; Anesthetics; Nervous System; Anesthetics, General; Opioid Anesthetics; CYP3A4 Inhibitors; Used as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
FDBD00614 Prilocaine Responsive image Anesthetics, Local; Anesthetics; Nervous System; Amides; Used as a local anaesthetic and is often used in dentistry.
43 , 5
FRAGNAME PDBID SIMILIRITY XSCORE SMILE HAC
2j62_ligand_1_0.mol2 2j62 1 -6.47 CC(C)C(=O)N 6
3g0i_ligand_3_6.mol2 3g0i 1 -6.41 CC(C)C(=O)N 6
1wdn_ligand_2_2.mol2 1wdn 1 -6.30 C(C(=O)N)C 5
5cal_ligand_2_20.mol2 5cal 1 -6.30 C(=O)(N)C(C)(C)C 7
4g4p_ligand_2_2.mol2 4g4p 1 -6.20 C(=O)(N)CC 5
4kqp_ligand_2_2.mol2 4kqp 1 -6.20 CCC(=O)N 5
2qpj_ligand_3_108.mol2 2qpj 1 -6.18 C(=O)(N)C(C)C 6
3m6p_ligand_3_45.mol2 3m6p 1 -6.17 C(C(=O)N)(C)C 6
4jt8_ligand_1_0.mol2 4jt8 1 -6.17 CC(C)(C)C(=O)N 7
1619 , 162