IUPAC name
1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
SMILES
CC(C)NCC(O)COC1=CC=CC2=C1C=CN2
Compound class
Antihypertensive Agents; Vasodilator Agents; Serotonin Antagonists; Adrenergic beta-Antagonists; Cardiovascular System; Beta Blocking Agents; Beta Blocking Agents, Non-Selective; CYP2D6 Inducers; CYP2D6 Inducers (strong);
Therapeutic area
For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Common name
Pindolol
IUPAC name
1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
SMILES
CC(C)NCC(O)COC1=CC=CC2=C1C=CN2
INCHI
InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3
FORMULA
C14H20N2O2
Common name
Pindolol
IUPAC name
1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
Molecular weight
248.321
clogP
2.534
clogS
-3.430
HBond Acceptor
2
HBond Donor
3
Total Polar Surface Area
57.28
Number of Rings
2
Rotatable Bond
6
| Drug ID | Common name | Structure CAS | SMILE | Frequency |
|---|---|---|---|---|
| FDBF00007 | propane |
|
C(C)C | 0.2412 |
| FDBF00041 | ethanol |
|
CCO | 0.1474 |
| FDBF00065 | ethylene glycol |
|
C(O)CO | 0.0265 |
| FDBF00094 | (2S)-propane-1,2-diol |
|
C(O)(CO)C | 0.0065 |
| FDBF00217 | 2-(isopropylamino)ethanol |
|
C(NC(C)C)CO | 0.0086 |
| FDBF02169 | 1H-indol-4-ol |
|
[nH]1c2c(c(ccc2)O)cc1 | 0.0003 |
| FDBF02171 | 2-(1H-indol-4-yloxy)ethanol |
|
C(CO)Oc1c2c([nH]cc2)ccc1 | 0.0003 |
| FDBF02172 | (2S)-1-(1H-indol-4-yloxy)propan-2-ol |
|
C(C(C)O)Oc1c2c([nH]cc2)ccc1 | 0.0003 |
16 ,
2
