Responsive image

Common name


Glutethimide

IUPAC name


3-ethyl-3-phenylpiperidine-2,6-dione

SMILES


CCC1(CCC(=O)NC1=O)C1=CC=CC=C1

Compound class


Hypnotics and Sedatives; Nervous System; Psycholeptics; Piperidinedione Derivatives; CYP2D6 Inducers; CYP2D6 Inducers (strong);

Therapeutic area


For the treatment of insomnia.

Common name


Glutethimide

IUPAC name


3-ethyl-3-phenylpiperidine-2,6-dione

SMILES


CCC1(CCC(=O)NC1=O)C1=CC=CC=C1

INCHI


InChI=1S/C13H15NO2/c1-2-13(10-6-4-3-5-7-10)9-8-11(15)14-12(13)16/h3-7H,2,8-9H2,1H3,(H,14,15,16)

FORMULA


C13H15NO2

Responsive image

Common name


Glutethimide

IUPAC name


3-ethyl-3-phenylpiperidine-2,6-dione

Molecular weight


217.264

clogP


2.861

clogS


-3.646

HBond Acceptor


2

HBond Donor


1

Total Polar
Surface Area


46.17

Number of Rings


2

Rotatable Bond


2

Drug ID Common name Structure CAS SMILE Frequency
FDBF00005 benzene Responsive image c1ccccc1 0.2824
FDBF00784 (3S)-3-ethylpiperidine-2,6-dione Responsive image C(C)C1C(=O)NC(=O)CC1 0.0007
FDBF00785 piperidine-2,6-dione Responsive image O=C1NC(=O)CCC1 0.0021
FDBF03038 (3S)-3-phenylpiperidine-2,6-dione Responsive image O=C1NC(=O)CCC1c2ccccc2 0.0003
4 , 1