Responsive image

Common name

5-phenyl-1H-tetrazole

IUPAC name

5-phenyl-1H-tetrazole

SMILES

c1c(cccc1)c2[nH]nnn2

Common name

5-phenyl-1H-tetrazole

IUPAC name

5-phenyl-1H-tetrazole

SMILES

c1c(cccc1)c2[nH]nnn2

INCHI

InChI=1S/C7H6N4/c1-2-4-6(5-3-1)7-8-10-11-9-7/h1-5H,(H,8,9,10,11)

FORMULA

C7H6N4

Responsive image

Common name

5-phenyl-1H-tetrazole

IUPAC name

5-phenyl-1H-tetrazole





Molecular weight

146.149

clogP

1.638

clogS

-2.228

Frequency

0.0027





HBond Acceptor

3

HBond Donor

1

Total Polar
Surface Area

54.46

Number of Rings

2

Rotatable Bond

1

Drug ID Common name Structure CAS Compound class Therapeutic area
FDBD00066 Valsartan Responsive image Antihypertensive Agents; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Lipid Modifying Agents; Cardiovascular System; Angiotensin II Antagonists, Plain; Agents Acting on the Renin-Angiotensin System; Angiotensin II Antagonists and Diuretics; Angiotensin II Antagonists and Calcium Channel Blockers; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Angiotensin II Receptor Antagonists; May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
FDBD00162 Olmesartan Responsive image Antihypertensive Agents; Angiotensin II Type 1 Receptor Blockers; Cardiovascular System; Angiotensin II Antagonists, Plain; Agents Acting on the Renin-Angiotensin System; Angiotensin II Antagonists and Diuretics; Angiotensin II Antagonists and Calcium Channel Blockers; Angiotensin II Receptor Antagonists; For the treatment of hypertension.
FDBD00543 Losartan Responsive image Antihypertensive Agents; Anti-Arrhythmia Agents; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Cardiovascular System; Angiotensin II Antagonists, Plain; Agents Acting on the Renin-Angiotensin System; Angiotensin II Antagonists and Diuretics; Angiotensin II Antagonists and Calcium Channel Blockers; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP3A4 Inhibitors; Angiotensin II Receptor Antagonists; Combined Inhibitors of CYP3A4 and P-glycoprotein; May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
FDBD00658 Candesartan Responsive image Antihypertensive Agents; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Cardiovascular System; Angiotensin II Antagonists, Plain; Agents Acting on the Renin-Angiotensin System; Angiotensin II Antagonists and Diuretics; Angiotensin II Antagonists and Calcium Channel Blockers; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C8 Inducers; Angiotensin II Receptor Antagonists; May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Candesartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors.
FDBD00882 Irbesartan Responsive image Antihypertensive Agents; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Cardiovascular System; Angiotensin II Antagonists, Plain; Agents Acting on the Renin-Angiotensin System; Angiotensin II Antagonists and Diuretics; Angiotensin II Antagonists and Calcium Channel Blockers; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C8 Inducers; CYP2D6 Inducers; CYP2D6 Inducers (strong); CYP3A4 Inhibitors; Angiotensin II Receptor Antagonists; For the treatment of hypertension, as well as diabetic nephropathy with an elevated serum creatinine and proteinuria (>300 mg/day) in patients with type 2 diabetes and hypertension. Irbesartan is also used as a second line agent in the treatment of congestive heart failure.
FDBD01145 Forasartan Responsive image Angiotensin Receptor Antagonists; Angiotensin II Receptor Antagonists; For the treatment of hypertension.
FDBD01149 Tasosartan Responsive image Cardiovascular System; Angiotensin II Antagonists, Plain; Agents Acting on the Renin-Angiotensin System; CYP3A4 Inhibitors; Angiotensin II Receptor Antagonists; Tasosartan is infrequently in the treatment of hypertension and heart failure.
FDBD01778 Fimasartan Responsive image Cardiovascular System; Angiotensin II Antagonists, Plain; Agents Acting on the Renin-Angiotensin System; Used for the treatment of hypertension and heart failure.
8 , 1
FRAGNAME PDBID SIMILIRITY XSCORE SMILE HAC
4bo9_ligand_1_1.mol2 4bo9 1 -7.13 c1(ccccc1)c1n[nH]nn1 11
4l34_ligand_1_1.mol2 4l34 1 -6.95 c1ccc(cc1)c1[nH]nnn1 11
1a8t_ligand_1_0.mol2 1a8t 1 -6.92 [nH]1nnnc1c1ccccc1 11
4de0_ligand_1_2.mol2 4de0 1 -6.77 c1([nH]nnn1)c1ccccc1 11
3g35_ligand_1_2.mol2 3g35 1 -6.74 c1cccc(c1)c1[nH]nnn1 11
4ddy_ligand_1_3.mol2 4ddy 1 -6.74 c1([nH]nnn1)c1ccccc1 11
4de2_ligand_1_4.mol2 4de2 1 -6.74 c1([nH]nnn1)c1ccccc1 11
4de1_ligand_1_2.mol2 4de1 1 -6.72 c1cc(ccc1)c1[nH]nnn1 11
128 , 13