Common name
1-methylimidazole
IUPAC name
1-methylimidazole
SMILES
n1(ccnc1)C
Common name
1-methylimidazole
IUPAC name
1-methylimidazole
SMILES
n1(ccnc1)C
INCHI
InChI=1S/C4H6N2/c1-6-3-2-5-4-6/h2-4H,1H3
FORMULA
C4H6N2
Common name
1-methylimidazole
IUPAC name
1-methylimidazole
Molecular weight
83.112
clogP
-0.631
clogS
-0.234
Frequency
0.0058
HBond Acceptor
0
HBond Donor
1
Total PolarSurface Area
19.67
Number of Rings
1
Rotatable Bond
0
| Drug ID | Common name | Structure CAS | Compound class | Therapeutic area |
|---|---|---|---|---|
| FDBD00976 | Econazole |
|
Antifungal Agents; 14-alpha Demethylase Inhibitors; Genito Urinary System and Sex Hormones; Dermatologicals; Gynecological Antiinfectives and Antiseptics; Imidazole and Triazole Derivatives; Antifungals for Topical Use; Antifungals for Dermatological Use; Imidazole Derivatives; CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors; | For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by . |
| FDBD01000 | Sertaconazole |
|
Antifungal Agents; Genito Urinary System and Sex Hormones; Dermatologicals; Gynecological Antiinfectives and Antiseptics; Imidazole and Triazole Derivatives; Antifungals for Topical Use; Antifungals for Dermatological Use; Imidazole Derivatives; | For the topical treatment of interdigital tinea pedis in immunocompetent patients 12 years of age and older, caused by . |
| FDBD01147 | Saprisartan |
|
Angiotensin II Receptor Antagonists; | Saprisartan is used in the treatment of hypertension and heart failure. |
| FDBD01320 | Bifonazole |
|
Antifungal Agents; Dermatologicals; Imidazole and Triazole Derivatives; Antifungals for Topical Use; Antifungals for Dermatological Use; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2B6 Inducers; Cytochrome P-450 CYP2B6 Inhibitors; CYP2B6 Inhibitors (strong); CYP2E1 Inhibitors; CYP2E1 Inducers; CYP2E1 Inducers (strong); CYP3A4 Inhibitors; | Used for the treatment of various topical fungal infections, including athlete's foot (tinea pedis). |
| FDBD01504 | Sulconazole |
|
Dermatologicals; Imidazole and Triazole Derivatives; Antifungals for Topical Use; Antifungals for Dermatological Use; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP2C9 Inducers; | Sulconazole solution 1.0% is indicated for the treatment of tinea cruris and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis; and for the treatment of tinea versicolor. Effectiveness has not been proven in tinea pedis (athlete's foot). |
| FDBD01587 | Isoconazole |
|
Genito Urinary System and Sex Hormones; Dermatologicals; Gynecological Antiinfectives and Antiseptics; Imidazole and Triazole Derivatives; Antifungals for Topical Use; Antifungals for Dermatological Use; Imidazole Derivatives; | |
| FDBD02023 | imidaclothiz |
|
Insecticide | Insecticide |
17 ,
2
| FRAGNAME | PDBID | SIMILIRITY | XSCORE | SMILE | HAC |
|---|---|---|---|---|---|
| 4fbe_ligand_1_3.mol2 | 4fbe | 1 | -5.92 | c1c[n+](c[nH]1)C | 6 |
| 4f9u_ligand_1_3.mol2 | 4f9u | 1 | -5.89 | c1c[n+](c[nH]1)C | 6 |
| 4mhy_ligand_1_3.mol2 | 4mhy | 1 | -5.88 | c1c[n+](c[nH]1)C | 6 |
| 4fai_ligand_1_3.mol2 | 4fai | 1 | -5.86 | C[n+]1cc[nH]c1 | 6 |
| 4f9v_ligand_1_3.mol2 | 4f9v | 1 | -5.82 | C[n+]1cc[nH]c1 | 6 |
| 4mhz_ligand_1_3.mol2 | 4mhz | 1 | -5.79 | C[n+]1cc[nH]c1 | 6 |
| 2afx_ligand_1_0.mol2 | 2afx | 1 | -5.78 | C[n+]1cc[nH]c1 | 6 |
105 ,
11
